Platelet concentrates for periodontal regeneration
Keywords:
Platelet concentrates, platelet rich plasma, platelet rich fibrin, injectable platelet-rich fibrin, titanium platelet- rich fibrinAbstract
Platelet concentrates are derivatives of blood that aid in haemostasis and wound healing after periodontal regenerative procedures. Its ability to act as a natural scaffold of growth factors has gained significance in many surgical procedures. This review article aims to briefly describe the different platelet concentrates used in the field of periodontology.
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References
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2. Deodhar AK, Rana RE. Surgical physiology of wound healing: a review. J Postgrad Med 1997; 43:52-6.
3. Harrison P. Platelet function analysis. Blood Rev 2005; 19:111-23.
4. Marx RE (2004) Platelet-rich plasma: evidence to support its use. J Oral Maxillofac Surg 62(4): 489-496.7.
5. Marx RE (2001) Platelet-rich plasma (PRP): what is PRP and what is not PRP? Implant Dent 10(4):225-228.
6. Matras H. [Effect of various fibrin preparations on reimplantation in the rat skin]. Osterr Z Stomatol 1970; 67: 338-359.
7. Ross R, Glomset J, Kariya B, Harker L. A platelet dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro. Proc Natl Acad Sci USA 1974; 71:1207-10.
8. Knighton DR, Ciresi KF, Fiegel VD, Austin LL, Butler EL. Classification and treatment of chronic nonhealing wounds. Successful treatment with autologous platelet-derived wound healing factors (PDWHF). Ann Surg 1986; 204: 322-330.
9. Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR. Platelet-rich plasma: Growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998; 85: 638-646.
10. Choukroun J, Adda F, Schoeffler C, Vervelle A. An opportunity in perio-implantology: The PRF. Implantodontie 2001; 42:55-62.
11. Bielecki T, Gazdzik TS, Szczepanski T. Re: “The effects of local platelet rich plasma delivery on diabetic fracture healing”. What do we use: Platelet-rich plasma or platelet-rich gel? Bone 2006; 39: 1388; author reply 1389.
12. Cieslik-Bielecka A, Gazdzik TS, Bielecki TM, Cieslik T. Why the platelet-rich gel has antimicrobial activity? Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007; 103: 303-305; author reply 303-305.
13. Cieslik-Bielecka A, Bielecki T, Gazdzik TS, Arendt J, Król W, Szczepanski T. Autologous platelets and leukocytes can improve healing of infected high-energy soft tissue injury. Transfus Apher Sci 2009; 41: 9-12.
14. Sacco L. Lecture, International academy of implant prosthesis and osteoconnection. Lecture 2006; 12: 4.
15. Dohan Ehrenfest DM, Del Corso M, Diss A, Mouhyi J, Charrier JB. Three-dimensional architecture and cell composition of a Choukroun’s platelet-rich fibrin clot and membrane. J Periodontol 2010; 81: 546-555.
16. Sohn DS. Lecture titled with sinus and ridge augmentation with CGF and AFG, Symposium on CGF and AFG. Tokyo, June 6, 2010.
17. Choukroun J. Advanced PRF and i-PRF: Platelet concentrate or blood concentrate? J Periodontal Med Clin Pract 2014; 1: 3.
18. Tunalı M, Özdemir H, Küçükodacı Z, Akman S, Fıratlı E. In vivo evaluation of titanium-prepared platelet-rich fibrin (T-PRF): a new platelet concentrate. Br J Oral Maxillofac Surg 2013; 51: 438-443.
19. Mourão CF, Valiense H, Melo ER, Mourão NB, Maia MD. Obtention of injectable platelets rich-fibrin (i-PRF) and its polymerization with bone graft: technical note. Rev Col Bras Cir 2015; 42: 421-423.
20. Smith RG, Gassmann CJ, Campbell MS. Platelet‑rich plasma: Properties and clinical applications. J Lanc Gen Hosp 2007; 2:73‑7.
21. Weibrich G, Kleis WK, Hafner G, Hitzler WE, Wagner W. Comparison of platelet, leukocyte, and growth factor levels in point‑of‑care platelet‑enriched plasma, prepared using a modified Curasan kit, with preparations received from a local blood bank. Clin Oral Implants Res 2003; 14:357‑62.
22. Anitua E. Plasma rich in growth factors: Preliminary results of use in the preparation of future sites for implants. Int J Oral Maxillofac Implants 1999; 14:529‑35.
23. Lekovic V, Camargo PM, Weinlaender M, Vasilic N, Kenney EB. Comparison of platelet‑rich plasma, bovine porous bone mineral, and guided tissue regeneration versus platelet‑rich plasma and bovine porous bone mineral in the treatment of intrabony defects: A re-entry study. J Periodontol 2002; 73:198‑205.
24. Wiltfang J, Schlegel KA, Schultze-Mosgau S, et al. Sinus floor augmentation with beta-tricalciumphosphate: does platelet-rich plasma promote its osseous integration and degradation? Clin Oral Impl Res. 2003; 14:213–8.
25. Suaid, F. F., Carvalho, M. D., Santamaria, M. P., Casati, M. Z., Nociti, F. H., Sallum, A. W., & Sallum, E. A. (2008). Platelet-Rich Plasma and Connective Tissue Grafts in the Treatment of Gingival Recessions: A Histometric Study in Dogs. Journal of Periodontology, 79(5), 888–895.
26. Torres J, Tamimi F, Martinez PP, et al. Effect of platelet-rich plasma on sinus lifting: a randomized-controlled clinical trial. J Clin Periodontol. 2009; 36:677–87.
27. Riaz, R., Ravindran, C., Ramkumar, & Nandakumar. (2010). Efficacy of Platelet Rich Plasma in Sinus Lift Augmentation. Journal of Maxillofacial and Oral Surgery, 9(3), 225–230.
28. Kutkut, A., Andreana, S., Kim, H., & Monaco Jr., E. (2012). Extraction Socket Preservation Graft Before Implant Placement with Calcium Sulfate Hemihydrate and Platelet-Rich Plasma: A Clinical and Histomorphometric Study in Humans. Journal of Periodontology, 83(4), 401–409.
29. Eskan MA, Greenwell H, Hill M, et al. Platelet-rich plasma-assisted guided bone regeneration for ridge augmentation: a randomized, controlled clinical trial. J Periodontol. 2014; 85:661–8.
30. Panda, S., Doraiswamy, J., Malaiappan, S., Varghese, S. S., & Del Fabbro, M. (2014). Additive effect of autologous platelet concentrates in treatment of intrabony defects: a systematic review and meta-analysis. Journal of Investigative and Clinical Dentistry, 7(1), 13–26.
31. Dutta SR, Singh P, Passi D, Patter P. Mandibular third molar extraction wound healing with and without platelet rich plasma: a comparative prospective study. J Maxillofac Oral Surg. 2015; 14:808–15.
32. Srinivas B, Rupa N, Halini Kumari K V, Prasad S, Varalakshmi U, Sudhakar K. Root coverage using subepithelial connective tissue graft with platelet-rich plasma in the treatment of gingival recession: A clinical study. J Pharm Bioall Sci 2015;7, Suppl S2:530-8.
33. Shivashankar VY, Johns DA, Vidyanath S, Kumar MR. Platelet rich fibrin in the revitalization of tooth with necrotic pulp and open apex. J Conserv Dent 2012; 15:395‑8.
34. Dohan Ehrenfest DM, de Peppo GM, Doglioli P, Sammartino G. Slow release of growth factors and thrombospondin-1 in Choukroun’s plateletrich fibrin (PRF): a gold standard to achieve for all surgical platelet concentrates technologies. Growth Factors 2009; 27: 63-69.
35. Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, et al. Platelet‑rich fibrin (PRF): A second‑generation platelet concentrate. Part I: Technological concepts and evolution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101: e37‑44.
36. Naik B, Karunakar P, Jayadev M, Marshal VR. Role of Platelet rich fibrin in wound healing: A critical review. J Conserv Dent 2013; 16:284‑93.
37. Vivek G, Vivek KB, Singh GP, Ashish M, Rhythm B. Regenerative potential of platelet rich fibrin in dentistry: Literature review. Asian J Oral Health Allied Sci 2011; 1:22‑8.
38. Sunitha Raja V, Munirathnam Naidu E. Platelet‑rich fibrin: Evolution of a second‑generation platelet concentrate. Indian J Dent Res 2008; 19:42‑6.
39. Pradeep AR, Rao NS, Agarwal E, Bajaj P, Kumari M, Naik SB. Comparative evaluation of autologous platelet‑rich fibrin and platelet‑rich plasma in the treatment of 3‑wall intrabony defects in chronic periodontitis: A randomized controlled clinical trial. J Periodontol 2012; 83:1499‑507.
40. Deepa D, Jain N. Gingival fenestration defect in the maxillary anterior region treated with coronally positioned flap using platelet‑rich fibrin membrane. J Interdiscipl Dent 2015; 5:140‑4.
41. Duan X, Lin Z, Lin X, et al. Study of platelet-rich fibrin combined with rat periodontal ligament stem cells in periodontal tissue regeneration. J Cell Mol Med. 2018;22(2):1047-1055.
42. Wang, Z., Han, L., Sun, T., Wang, W., Li, X., & Wu, B. (2019). Preparation and effect of lyophilized platelet-rich fibrin on the osteogenic potential of bone marrow mesenchymal stem cells in vitro and in vivo. Heliyon, 5(10), e02739.
43. Al-Maawi, S., Herrera-Vizcaíno, C., Orlowska, A., Willershausen, I., Sader, R., Miron, R. J., … Ghanaati, S. (2019). Biologization of Collagen-Based Biomaterials Using Liquid-Platelet-Rich Fibrin: New Insights into Clinically Applicable Tissue Engineering. Materials, 12(23), 3993.
44. Atchuta A, Gooty JR, Guntakandla VR, Palakuru SK, Durvasula S, Palaparthy R. Clinical and radiographic evaluation of platelet-rich fibrin as an adjunct to bone grafting demineralized freeze-dried bone allograft in intrabony defects. J Indian Soc Periodontol. 2020;24(1):60-66.
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