THE EFFECT OF PROBIOTIC MOUTHRINSE ON PLAQUE AND GINGIVAL INFLAMMATION
Abstract
This study evaluated the effect of a Probioticmouthrinse containing nisin, a bacteriocin extractedfrom Lactococcus lactis on dental plaque andgingivitis in young adult population.A group of 32 subjects were randomly assignedinto two groups of 16 each. The first group startedusing the control mouthrinse (placebo) for 2 weeksfollowed by a washout period of 4 weeks. This groupthen used the test mouthrinse (Probiotic) for afurther duration of 2 weeks. The second groupfollowed a similar protocol as the first except thatthis group started with the test mouthrinse(Probiotic). Plaque Index (PI) and Gingival Index(GI) were recorded at baseline and after 2 weeks foreach group. All subjects were given full mouthprophylaxis after each measurements.The results of this study showed that rinsingwith Probiotic mouthrinse resulted in a statisticallysignificant reduction of plaque accumulation andgingivitis compared to rinsing with placebo. Theresults indicated that Probiotic mouthrinsecontaining nisin had the potential of inhibitingplaque accumulation and was effective in reducinggingivitis.
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